Stewart Gandolf (Healthcare Success): Good day—welcome to our podcast. And at the moment I’ve considered one of my longest-standing mates…

Michael—how lengthy have we identified one another? Like 30 years virtually?

Dr. Dr. Michael Leon (Reminiscence Air): In all probability 30. Yeah.

Stewart Gandolf (Healthcare Success): One thing like that.

Dr. Michael Leon (Reminiscence Air): 25 anyway, for positive.

Stewart Gandolf (Healthcare Success): Yeah. We met one another after we have been 10 years previous.

So I met Michael in one other life, one other world. However Michael and I grew to become mates. We’ve finished some enjoyable issues collectively. We labored collectively making an attempt to assist a really fascinating machine and system for consuming issues. We labored in autism remedy…

Michael’s influence on my life has been each skilled and private. He helped my daughter when she turned out to be on the autism spectrum.

So, Michael—you’re considered one of my pricey mates. Welcome to my podcast. I’m so comfortable to have you ever.

Dr. Michael Leon (Reminiscence Air): Thanks for having me. Good to see you on-line.

Stewart Gandolf (Healthcare Success): I do know. You’re not that distant—what, 20 minutes? We must always have finished this face-to-face. Subsequent time.

So, Michael— your background higher than me. We talked about your touring from being a lifeguard to cleansing rat cages… So I do know you all the best way again. After which to professor—it was most likely linear, proper? Lifeguard, rat cleansing, professor at UCI?

Dr. Michael Leon (Reminiscence Air): It went precisely like that.

Stewart Gandolf (Healthcare Success): However your life’s work is in sensory… I simply put it as sensory stimulation. I feel you name it environmental enrichment.

By the best way—this episode is particular, so I extremely suggest you keep to the tip of it. All of them are good, however this one’s going to be actually good.

So Michael, give us a touch of what we’re speaking about at the moment. What’s environmental enrichment or sensory stimulation, as I name it? What are we speaking about right here?

Dr. Michael Leon (Reminiscence Air): So it seems that your mind wants a substantial amount of stimulation from the surface world as a way to keep wholesome. And most of us suppose we get loads of stimulation—, we have now tv, we’ve acquired music, we’re speaking to folks.

However the one sense that we’re disadvantaged chronically in our prosperous fashionable world is our odor-sensing system—additionally known as the olfactory system. And when you don’t get sufficient olfactory stimulation, the reminiscence and cognitive elements of your mind begin to deteriorate, as does the emotional a part of your mind. So that you’re extra susceptible to melancholy and extra susceptible to shedding your reminiscence.

Any time you don’t get sufficient olfactory stimulation, your reminiscence goes. And you’ll see that when folks become old: their olfactory capability decreases. By the point you hit 60, it begins to fall off the desk. And hand-in-hand with that, your capability to recollect issues additionally falls.
So your capability to scent is intently tied to your capability to recollect issues. Even a chronically stuffed nostril will trigger each a lack of the power to scent issues and a lack of reminiscence.

And every little thing else that causes lack of olfaction—sense of scent—additionally has that drawback. Individuals who’ve had COVID-19… just about everyone had olfactory loss. They usually’ve had reminiscence loss.

When researchers from Oxford College imaged their brains, what they discovered is that the olfactory system was deteriorated months after folks had recovered from gentle COVID. And their reminiscence was additionally deteriorating. So folks with lengthy COVID have this extended drawback: olfactory loss and reminiscence loss.

And just about each medical drawback that you’ve—we’ve counted 157 of them—from schizophrenia to most cancers to coronary heart illness to melancholy—all of them have olfactory loss and elevated irritation. And we predict it is a vital a part of what’s happening now.
And everyone is chronically disadvantaged of olfactory stimulation of their each day lives. If everyone takes a deep breath now, my guess is that no one will scent something.

Stewart Gandolf (Healthcare Success): Yeah—I simply tried and nothing occurred.

Dr. Michael Leon (Reminiscence Air): And the human mind advanced at a time when there have been loads of odors. Actually, no one ever took a bathe—ever. So the human mind advanced to have affiliation with a substantial amount of olfactory stimulation. And now we’re not getting very a lot in any respect—coupled with a lot of drugs that intervene with olfaction. Stress—even stress while you’re a toddler—can have an effect on your capability to scent while you’re an grownup.

There are lots of issues related to olfactory loss and elevated irritation. And we’re beginning to deal with that in a really efficient method. So when folks lose their reminiscence as they become old… and when you ask anyone over 60, they’ll discuss issues with reminiscence. Their capability to scent declines, however when you give them olfactory enrichment—loads of olfactory stimulation—you may get a dramatic improve of their capability to recollect issues.

Stewart Gandolf (Healthcare Success): There’s a lot to unpack there. I’ll attempt to come again to what you simply stated a minute in the past—as a result of I’d like to speak extra about reversal versus simply slowing, which is thrilling.

However earlier than I get there: once I first met you, we talked about different kinds of sensory stimulation—visible, auditory, tactile, in addition to olfactory and style. We didn’t discuss style a lot, however I’m positive that’s a part of it too.

However I feel over time—even since I’ve identified you—the concentrate on scent appears to be increasingly major. Is {that a} good abstract of your life’s work?

Dr. Michael Leon (Reminiscence Air): Yeah. I feel most individuals discover it stunning as a result of they contemplate the olfactory system their least vital sense. If you happen to ask folks which sense they’d be keen to surrender, virtually everyone says the olfactory system. They suppose it’s only a good factor to find out whether or not the wine you’re consuming is nice.

However the central significance of olfactory stimulation to the well being of your mind is basically not usually appreciated. And due to that, individuals are going by means of their lives with out a lot olfactory stimulation, and their mind begins deteriorating—making it rather more susceptible to all types of different neurological and somatic issues.

Stewart Gandolf (Healthcare Success): Earlier than I get again to the questions we deliberate: I bear in mind speaking about—do I bear in mind this accurately?—that again in your earlier days, you’ll give rats stimulation, reduce them up, and take a look at their brains extra deeply. And those that had rather more stimulation had larger brains.

Is that true? Or was it extra synapses—what was it that you simply discovered within the earlier phases?

Dr. Michael Leon (Reminiscence Air): So what we have been is early studying. It seems that human infants study to be interested in the odor of their mom—or another odor you place involved with them—on the primary day of life. Once they simply come out, that is the very first thing they study concerning the world. And it’s a really highly effective sort of studying.

And it does change their mind. There are anatomical modifications, neurophysiological (electrical) modifications, neurotransmitter modifications, and behavioral modifications. So on the second day of life, you possibly can check them—these human newborns—and so they bear in mind the odor of their mom and so they’re interested in it. And that is, we predict, the primary foundation for the maternal-infant bond.

Stewart Gandolf (Healthcare Success): Wow. Superb. So the environment has modified radically. Has the mind modified too over time—evolutionarily? Is there any proof to that?

Dr. Michael Leon (Reminiscence Air): In our fashionable prosperous world, we simply don’t get a lot olfactory stimulation. And due to that, we’re very susceptible to neurological issues and somatic issues as effectively.

We predict it is a difficult interplay between a rise in irritation that happens within the mind and the physique with out olfactory stimulation. One of many issues that we discovered—and others, lots of of others, have discovered—is that nice odors really lower irritation.

Irritation, as , underlies most of the damaging forces within the mind and physique. And so we predict everyone wants it. And what we’re discovering is that not solely older adults, however middle-aged and youthful adults are actually on this—as a result of everyone needs to have a pointy thoughts. And it seems this may assist folks, we predict, all through their lives.

Stewart Gandolf (Healthcare Success): That’s wonderful.

We’ve talked about folks being sensory-deprived. I’ve to provide a private remark right here—and I don’t suppose I’ve ever informed you this half, Michael. I’ve each a deviated septum and persistent allergic reactions. I’ve taken Claritin, I’ve taken Zyrtec… and I lastly began utilizing the nasal steroid with the allergy spray, with the capsule, and now I can breathe and scent higher. It took that a lot firepower—which stinks—however I can scent issues now.

My spouse is laughing at me as a result of she’ll inform me, “You scent every little thing.” I’m like, “I’ve to—Michael says…”

However I’m experiencing the world totally different as a result of I used to be chronically congested in a single kind or one other for years. I wasn’t fully congested, however my sense of scent has lastly modified. The neti pot helped somewhat, however once I came upon I may do the steroid and the antihistamine on the identical time with out, , dying—it’s been life-changing for me. It actually has.

Dr. Michael Leon (Reminiscence Air): That’s good to know. And it could protect your mind as you become old.

Stewart Gandolf (Healthcare Success): Yeah. So I’ve to share one thing with our viewers right here. I nonetheless have my little vials—and Michael could acknowledge a few of these.

After I had COVID, I known as Michael as a result of I learn about this. I stated, “Michael—they are saying wait six months earlier than you get sensory stimulation. How lengthy ought to I wait?” I’m assuming under no circumstances.

He’s like, “Go to Amazon now and purchase…” Was it rose, lemon, sage, and one thing else? I neglect. However anyway, I purchased them—and I nonetheless have them. It’s wonderful—there’s one thing calming about it. It’s not psychotropic, I don’t suppose, but it surely’s such an instantaneous rush of… I don’t know, emotion.

What’s behind this? Individuals confuse this with aromatherapy, which is sort of associated, however not the identical factor.

Dr. Michael Leon (Reminiscence Air): Over the course of evolution, the mind wants a substantial amount of olfactory stimulation. And as a way to ensure that folks get sufficient, it made us interested in nice odors. So we get an actual rush and a sense of leisure and pleasantness—and we’re attracted to those nice odors.

Actually, you’ve gotten a reflex: while you scent nice odors, you mechanically begin to sniff it with out considering. It’s an actual reflex. And while you’re uncovered to disagreeable odors, the mind stops you from respiration instantly.

Stewart Gandolf (Healthcare Success): Wow—that’s cool.

So we’re going to speak about two issues at the moment. I’d like to speak about autism in somewhat bit as a result of I feel that’s actually vital—and that’s additionally some new stuff arising. However the machine known as Reminiscence Air, so let’s begin there.

Michael and I, by the best way, pitched a present to Hollywood. We had an agent and an legal professional. We really acquired to fulfill with twentieth Tv—and we have been shut, Michael. We have been actually shut. Sometime we’ll do this once more.

However let’s speak concerning the proof about olfactory… You’ve talked about some broad issues, however discuss a number of the scientific proof about olfactory enrichment. Let’s begin with mind well being total after which discuss reminiscence.

Dr. Michael Leon (Reminiscence Air): Okay. I’ll begin with the truth that lab animals are stored in an ordinary field cage alone, with not a lot to do and little or no stimulation. These animals look okay—they will study, bear in mind, have motor expertise, social interactions are regular.

However when you take these rats or mice from an ordinary field cage and put them in a a lot larger enclosure with loads of mates and loads of issues to do, their brains turn out to be rather more complicated and rather more succesful. They study higher, bear in mind higher, have higher motor expertise—every little thing about their habits improves.

Much more spectacular: scientists have made animal fashions of each human neurological dysfunction you possibly can consider. They specific human-type signs after they’re in the usual field cage—little or no stimulation. However while you put them in an enriched atmosphere—larger place, extra mates, extra issues to do—they lose many or all of their neurological signs.

It’s so highly effective {that a} rat injected with a neurotoxin like lead has higher cognitive capability than a rat who hasn’t been injected with any toxin, however resides in an ordinary cage.

So we thought possibly this might profit kids with autism. There’s additionally a state of affairs in Romania with human infants that prompted our curiosity. Throughout Nicolae Ceausescu’s regime, he banned contraceptives and ruined the economic system. Individuals had loads of kids however no cash, so that they introduced them to state orphanages.

Within the orphanages, kids have been put in cages—alone, remoted—identical to rats in laboratories. Once they got here out, relatively than 1%–2% having autism, a few third had autism signs. We predict as a result of they have been residing beneath restricted sensory stimuli.

When some kids have been positioned into full-time foster care—an enriched atmosphere—they misplaced many or all of their autism signs.

So we tried to duplicate this with kids with autism in Irvine. We gave dad and mom a equipment with many odors—plus visible stimulation, auditory stimulation, motor stimulation, and tactile stimulation. We had a management group.

After six months, 42% had a serious enchancment in signs in comparison with 7% with customary care. We additionally discovered an eight-point improve in IQ in comparison with virtually nothing with customary care, elevated receptive language, important enchancment in irregular responses to sensory stimuli. After six months, 21% of significantly affected kids have been not thought of to have traditional autism in comparison with 0% on customary care.

We went on to do different research. One mother or father was so impressed that he fashioned an organization and developed it for folks world wide. It’s known as Mendability, and individuals are utilizing it everywhere in the world with good advantages.

We predict this may be improved additional by giving olfactory enrichment. And we now have a tool the place we predict we are able to do that with none effort.

Stewart Gandolf (Healthcare Success): Earlier than I transfer away from that and begin speaking about reminiscence loss: Michael’s been a really huge a part of my private life.

My daughter—when she was a couple of years previous—started displaying indicators of autism spectrum, and our world simply collapsed. It was terrible. She hadn’t been that method at first and began displaying indicators round two, which I feel is fairly traditional.

Michael launched me to the therapist who innovated this. The wonderful factor… I’ll condense a two- or three-year story: scents like strawberry, after which touching her face—there was one thing about doing that. The primary time we did it, her eyes rolled behind her head. She was the happiest she’d been in months. It was wonderful.

So we did that along with her for years—so long as she allowed us to. She stopped permitting us when she acquired older.

She’s a senior in school. She’s about to graduate. She nonetheless has challenges, however her life trajectory is wildly higher than it will have been with out this. And you could possibly supply me $10 million, Michael, however not expose her to this—and I wouldn’t take it. I wouldn’t return and roll the cube and hope it seems okay. We hear these tales over and over.

Dr. Michael Leon (Reminiscence Air): It actually revolutionizes the best way these kids develop and alters the course of their life. It’s actually vital that folks learn about this as a result of customary care takes months—possibly a 12 months, I’ve heard two years—earlier than you may get a prognosis. Then you definately battle with college techniques and insurance coverage firms to get it funded.

And knowledge from customary care comes from universities, however most individuals don’t get it from universities—they get it from personal firms hiring individuals who could or will not be significantly good. Outcomes aren’t significantly good.

Commonplace care can also be centered simply on social interactions, whereas the enrichment technique offers with all their auxiliary signs, which will be as severe because the social interplay issues.

Stewart Gandolf (Healthcare Success): Yeah. I’ll give the newbie viewpoint on this, Michael.

We determined to do every kind of sensory stimulations. We did imaginative and prescient remedy, studying courses… I took her ice skating when she hated it. Bike using, swimming… However I nonetheless really feel just like the olfactory stimulation with the tactile contact—that was the core of all of it.

We skipped the varsity program solely as a result of they needed to place her in particular ed… one other story. She was type of the star child of her class, and I insisted on common college. We put her in a personal college. Two years later one of many identical lecturers stated, “Oh my God, you made the appropriate choice.”

In order that’s value exploring. And when you’re listening to this on the streaming service, you possibly can go to HealthcareSuccess.com, seek for this podcast. Michael—on the finish of this, it is advisable give me hyperlinks to science for each autism and reminiscence that I can put within the present notes. It’s actually vital. I prefer to make these episodes significant and meaty—not simply listening to us speak, however getting some proof can be superior.

So I shared a really private story there. However like I stated, for hundreds of thousands of {dollars} I wouldn’t spin the bottle and keep away from doing this. It was instantly impactful. I extremely suggest it. I’ve beneficial a number of folks to do that.
And this little bottle of strawberry is a kind of leftovers from these days. I nonetheless have it—possibly 25% left. It goes slowly.

So anyway—let’s discuss reminiscence. The present at the moment is basically about reminiscence, and we’ve acquired one other half hour, so I’m going to spend time on this.

In principle, you could possibly take this little bottle and scent it a number of instances a day and get presumably the identical consequence—it’s simply no one does that, proper?

So the machine—which we’ll discuss in a second—is a method of doing that passively. People—even motivated ones—are horrible at following by means of, Michael.

Dr. Michael Leon (Reminiscence Air): Yeah. An exquisite growth is a examine out of South Korea that used olfactory stimulation to extend the reminiscence of individuals with dementia—Alzheimer’s illness. Individuals have tried every kind of issues; billions of {dollars} spent; lots of of scientific trials. The most recent anti-Alzheimer’s medication are actually ineffective—tiny slowing of decline, nothing you’ll discover. Very costly, unsafe—mind bleeds, mind shrinkage, dying. Onerous to get; it’s a must to go to the hospital for infusions. Worst of all worlds.

Right here you’ve gotten one thing extremely efficient. On 5 assessments of reminiscence, enhancements have been as much as 300% higher than controls. Melancholy signs have been relieved by 325%. Individuals had these enhancements inside 15 days.

The issue is: to get these enhancements, they needed to give them 40 odors twice a day—and no one will do this. Individuals received’t even take low-dose aspirin after a coronary heart assault.
So we devised a tool—we name it Reminiscence Air. It sits in your nightstand and places out 40 nice odors twice an evening. We predict this may revolutionize the best way Alzheimer’s illness is handled.

We’re additionally discovering folks of their 40s and 50s have an interest—they need to hold their minds sharp. We predict individuals are chronically disadvantaged of olfactory stimulation all through their lives, and olfactory enrichment—40 odors twice an evening—will hold the mind wholesome, not only for reminiscence however for emotion and melancholy signs.

The olfactory system has the one devoted superhighway entry to the reminiscence facilities and emotional facilities of the mind. All different senses must undergo aspect streets and consequently don’t have as a lot influence.
So all through life, we predict everyone wants rather more olfactory stimulation, and our machine can present that.

And a pair weeks in the past, Time journal named us as an invention of the 12 months in well being and wellness for 2025. We’ve additionally acquired an award from the American Psychological Affiliation for our work with autism.

Stewart Gandolf (Healthcare Success): That’s wonderful. I’d love all these hyperlinks—give me as many as you need. I’ll put them on there.

Dr. Michael Leon (Reminiscence Air): Okay.

Stewart Gandolf (Healthcare Success): Let’s speak—knowledge you’ve seen, or anecdotes up to now. The machine has gone by means of alpha, beta… a lot of growth. It seems constructing a tool from scratch is tougher than most individuals suppose.

Full disclosure: I’m a minority investor on this product. After working with Michael for all these years, I couldn’t let it go by. So we’ve been speaking about this for 3 or 4 years, proper? Numerous levels of engineering. It takes quite a bit to construct a tool that really works.

Dr. Michael Leon (Reminiscence Air): Yeah. Units are difficult. And it’s not only a machine—it has a disposable. Each month you get a brand new odorant belt with 40 odors, and you place it in as a result of it makes use of up the odors over the course of the month.

All this stuff must be developed individually. Each little half issues. You’re constructing an actual factor. It’s not one molecule—it’s difficult in a dozen methods, possibly a number of dozen methods.

So it’s taken years to get to the purpose the place we are able to manufacture it. Manufacturing is an entire different factor. We tried America—that didn’t work. China—that didn’t work. We lastly discovered three teams in Malaysia, and so they’re doing an impressive job.

We needed to search to search out individuals who would take it significantly and have been competent sufficient to do it precisely proper—as a result of when you’re off by somewhat bit, it’s ineffective.

We lastly employed a gaggle of engineers—former senior Apple designers and engineers—so that they made a phenomenal, useful, manufacturable machine. We’re actually pleased with the way it got here out.

Stewart Gandolf (Healthcare Success): That’s superior. I’m actually glad to listen to that.

Again to the proof: we talked broadly about olfactory. I don’t know if you wish to share anything—or simply anecdotes—as a result of we’re going to do scientific trials ultimately, proper? Any proof you possibly can discuss now about early returns or broadly with Alzheimer’s?

Dr. Michael Leon (Reminiscence Air): One fellow has Parkinson’s illness—and about half of individuals with Parkinson’s develop dementia. After 4 to 6 months on the machine, he took a reminiscence check at the start and after six months. He was a geologist. He greater than doubled his reminiscence rating inside six months. That’s fairly wonderful.

Individuals with Parkinson’s have olfactory loss and elevated irritation—the entire track and dance.

One other individual stated her husband all the time needed to full her sentences as a result of she couldn’t bear in mind the phrase. After a month utilizing Reminiscence Air, he stated, “, I haven’t been having to finish your sentences because you began utilizing this factor.”

Stewart Gandolf (Healthcare Success): I don’t know… that’s good.

Dr. Michael Leon (Reminiscence Air): She additionally stated she was very clumsy—she’d drop a vitamin capsule or a spoon daily. Since utilizing this, she stated she hasn’t dropped something.

There’s a direct connection between the olfactory system and the cerebellum, which controls motor coordination. We predict what we’re doing is making that normalized and wholesome once more.

We’re getting very constructive feedback. Individuals are sleeping a lot better—on common, 22 minutes further sleep, which is big. We predict this will likely turn into actually vital.
As folks become old, deep sleep diminishes, and in lots of older adults there isn’t a lot deep sleep in any respect. Throughout deep sleep, your mind washes out all of the waste that’s accrued—by means of the glymphatic system. It pushes it out to the entrance of the mind and thru the holes within the cranium the place the olfactory system is available in.

In case you have a robust system throughout deep sleep, you possibly can eliminate toxins and waste. However when folks become old, you don’t have this washout as a result of the olfactory system is obstructing the best way. Except you’ve gotten a robust push, it doesn’t get out of the mind.

So that you’re marinating the olfactory system in toxins and waste, which triggers irritation. And irritation accompanies greater than 139 medical issues, neurological and somatic.

We predict many issues impair the lymphatic system so it might probably’t push out waste, and the mind is marinating in its personal waste. That could be why these issues have olfactory dysfunction—as a result of it will increase irritation that damages the olfactory system and prevents waste from being cleared. We predict this could possibly be an vital mechanism to know what’s happening.

Stewart Gandolf (Healthcare Success): Wow—that’s wonderful.

And it’s humorous as a result of I bear in mind instances while you’ve stated, “I’d prefer to imagine that, however the scientist in me doesn’t,” proper?

A few of our listeners are scientists, medical doctors, researchers. What would you say to them in the event that they’re tremendous skeptical? The place would you direct them? I’ll have analysis within the present notes—anything?

Dr. Michael Leon (Reminiscence Air): This is a gigantic literature. There at the moment are 11 main epidemiological research displaying that by midlife, your all-cause mortality—whether or not you die for any cause—will be precisely predicted by your capability to scent issues.

Stewart Gandolf (Healthcare Success): Wow. I’m positive no one is aware of that.

Dr. Michael Leon (Reminiscence Air): And there are about 20 research displaying that when you improve olfactory stimulation—and never only one odor; it’s a number of odors which are vital—you enhance both reminiscence and/or the elements of the mind that management reminiscence.

So it’s not one examine or a pair research—it’s an enormous literature that every one says the identical factor: lack of olfaction damages the mind, and elevated olfactory stimulation will increase mind well being.

Stewart Gandolf (Healthcare Success): So our podcast is basically about innovation and advertising in healthcare. We’ve talked about innovation. I do know you’re not dealing with the advertising, however you’re already promoting these, proper? There’s loads of demand. Any feedback on the advertising?

Dr. Michael Leon (Reminiscence Air): It’s not my space of experience, however we’ve bought out our first cargo. We’ve acquired one other 10,000 approaching a ship. We bought out the primary group with none ads.

There’s been huge curiosity—over 200 media tales world wide: podcasts, TV, radio, newspapers, magazines, on-line—every little thing. Individuals are actually .

I’m fascinated that they’re fascinated. With new concepts, they usually get ignored or individuals are so skeptical they received’t even contemplate them. However right here, individuals are drawn to it. They’re not skeptical—one thing about it hits dwelling.

Stewart Gandolf (Healthcare Success): Our expertise collectively engaged on the machine and program for consuming issues… we’d get constructive science and no one cared. Or the journalistic method is “stability”—at some point a constructive story, the following day 10 folks saying the alternative.

There’s a lot confusion and misinformation on the market. Even with autism—actually arduous.
However with this, what’s the draw back? You’re smelling nice smells at night time. It’s passive.

Dr. Michael Leon (Reminiscence Air): Yeah. And I feel there are some concepts the place folks simply go, “Sure—that is smart.” That is considered one of them.

Different stuff you’ve described, folks go, “Who is aware of—possibly sure, possibly no.”
We actually have the one efficient remedy for anorexia, bulimia, binge consuming dysfunction, and weight problems—even weight problems in kids—and many years later it’s nonetheless not right here.

Stewart Gandolf (Healthcare Success): Yeah—many years later. We labored on that, proper? Many years later, it’s nonetheless not right here. That’s considered one of my most irritating issues professionally. However a minimum of I acquired to put money into Reminiscence Air.

In order we’re wrapping up: it’s about a number of odors. What does it price? What’s the month-to-month factor? How do I purchase it?

Dr. Michael Leon (Reminiscence Air): You go to MemoryAir.com. That’s the one place you may get it at this level—solely in the USA. We don’t have the power to supply it elsewhere. You purchase the machine for $799, and each month you get a brand new odorant belt that’s $39, shipped mechanically. You don’t must do something.

If you get it, you place the odorant belt in, press a button while you fall asleep. After a delay, it’s going to go on and can go on at the moment eternally. You simply get a brand new belt each month as a result of it makes use of up the odors. You place it in, shut the door, and fall asleep. That’s it.

Stewart Gandolf (Healthcare Success): That’s wonderful. And I bear in mind the trials and tribulations of attending to do it that simply. It’s not a simple street—don’t let anyone child you.

And I’m positive availability will change, however proper now it’s MemoryAir.com. I’m actually enthusiastic about this. I get alternatives to put money into issues fairly often, and this is likely one of the only a few the place I did it versus simply common inventory stuff.

However I’m emotionally concerned. I imagine within the concept. I imagine within the science. And I did a horrible job setting this up—I didn’t even inform them about your background with UCI and your professorship and your years of science. However I’ll put that within the present. Be sure you give me a replica of your bio.

Dr. Michael Leon (Reminiscence Air): So Alan will all the time introduce me by saying I’m one of many—in response to a survey from Stanford College Medical College—ranked among the many prime 1% of scientists on this planet.

Stewart Gandolf (Healthcare Success): That’s fairly good.

Dr. Michael Leon (Reminiscence Air): Yeah.

Stewart Gandolf (Healthcare Success): So that you’re not simply promoting stuff. You’re not simply promoting stuff on the carnival .In order that’s… that’s… The rest we missed—knowledge, proof, breakthrough, utility to different illnesses—anything you need to share as we wrap up?

Dr. Michael Leon (Reminiscence Air): The factor that stunned me most is how many individuals who aren’t older adults have an interest and have ordered one—folks of their 30s, 40s, and 50s. Not fairly biohackers—they only need further assist with their mind.

Stewart Gandolf (Healthcare Success): Assuming any individual’s acquired a partner or accomplice—is the machine sturdy sufficient to learn each, or do you purchase two?

Dr. Michael Leon (Reminiscence Air): I like to recommend two as a result of the throw is about 4 ft. Except you sleep on a single mattress, it most likely received’t work for each. If you happen to can afford it, two can be optimum—one on both sides of the mattress.

We now have considered one of these California king beds the place it’s miles between us—so we have now two of them and that works out very well.

Stewart Gandolf (Healthcare Success): I’m going to modify to a twin so I can simply purchase one and be low cost. Probably not.

All proper, Michael—it’s been enjoyable speaking to you. Congratulations. It should be actually thrilling to have your life’s work come collectively into one thing folks can really use.

Dr. Michael Leon (Reminiscence Air): Yeah. It’s an actual pleasure to see it come collectively.

Stewart Gandolf (Healthcare Success): Superior. Thanks.

Stewart Gandolf (Healthcare Success): Good day—welcome to our podcast. And at the moment I’ve considered one of my longest-standing mates…

Michael—how lengthy have we identified one another? Like 30 years virtually?

Dr. Dr. Michael Leon (Reminiscence Air): In all probability 30. Yeah.

Stewart Gandolf (Healthcare Success): One thing like that.

Dr. Michael Leon (Reminiscence Air): 25 anyway, for positive.

Stewart Gandolf (Healthcare Success): Yeah. We met one another after we have been 10 years previous.

So I met Michael in one other life, one other world. However Michael and I grew to become mates. We’ve finished some enjoyable issues collectively. We labored collectively making an attempt to assist a really fascinating machine and system for consuming issues. We labored in autism remedy…

Michael’s influence on my life has been each skilled and private. He helped my daughter when she turned out to be on the autism spectrum.

So, Michael—you’re considered one of my pricey mates. Welcome to my podcast. I’m so comfortable to have you ever.

Dr. Michael Leon (Reminiscence Air): Thanks for having me. Good to see you on-line.

Stewart Gandolf (Healthcare Success): I do know. You’re not that distant—what, 20 minutes? We must always have finished this face-to-face. Subsequent time.

So, Michael— your background higher than me. We talked about your touring from being a lifeguard to cleansing rat cages… So I do know you all the best way again. After which to professor—it was most likely linear, proper? Lifeguard, rat cleansing, professor at UCI?

Dr. Michael Leon (Reminiscence Air): It went precisely like that.

Stewart Gandolf (Healthcare Success): However your life’s work is in sensory… I simply put it as sensory stimulation. I feel you name it environmental enrichment.

By the best way—this episode is particular, so I extremely suggest you keep to the tip of it. All of them are good, however this one’s going to be actually good.

So Michael, give us a touch of what we’re speaking about at the moment. What’s environmental enrichment or sensory stimulation, as I name it? What are we speaking about right here?

Dr. Michael Leon (Reminiscence Air): So it seems that your mind wants a substantial amount of stimulation from the surface world as a way to keep wholesome. And most of us suppose we get loads of stimulation—, we have now tv, we’ve acquired music, we’re speaking to folks.

However the one sense that we’re disadvantaged chronically in our prosperous fashionable world is our odor-sensing system—additionally known as the olfactory system. And when you don’t get sufficient olfactory stimulation, the reminiscence and cognitive elements of your mind begin to deteriorate, as does the emotional a part of your mind. So that you’re extra susceptible to melancholy and extra susceptible to shedding your reminiscence.

Any time you don’t get sufficient olfactory stimulation, your reminiscence goes. And you’ll see that when folks become old: their olfactory capability decreases. By the point you hit 60, it begins to fall off the desk. And hand-in-hand with that, your capability to recollect issues additionally falls.
So your capability to scent is intently tied to your capability to recollect issues. Even a chronically stuffed nostril will trigger each a lack of the power to scent issues and a lack of reminiscence.

And every little thing else that causes lack of olfaction—sense of scent—additionally has that drawback. Individuals who’ve had COVID-19… just about everyone had olfactory loss. They usually’ve had reminiscence loss.

When researchers from Oxford College imaged their brains, what they discovered is that the olfactory system was deteriorated months after folks had recovered from gentle COVID. And their reminiscence was additionally deteriorating. So folks with lengthy COVID have this extended drawback: olfactory loss and reminiscence loss.

And just about each medical drawback that you’ve—we’ve counted 157 of them—from schizophrenia to most cancers to coronary heart illness to melancholy—all of them have olfactory loss and elevated irritation. And we predict it is a vital a part of what’s happening now.
And everyone is chronically disadvantaged of olfactory stimulation of their each day lives. If everyone takes a deep breath now, my guess is that no one will scent something.

Stewart Gandolf (Healthcare Success): Yeah—I simply tried and nothing occurred.

Dr. Michael Leon (Reminiscence Air): And the human mind advanced at a time when there have been loads of odors. Actually, no one ever took a bathe—ever. So the human mind advanced to have affiliation with a substantial amount of olfactory stimulation. And now we’re not getting very a lot in any respect—coupled with a lot of drugs that intervene with olfaction. Stress—even stress while you’re a toddler—can have an effect on your capability to scent while you’re an grownup.

There are lots of issues related to olfactory loss and elevated irritation. And we’re beginning to deal with that in a really efficient method. So when folks lose their reminiscence as they become old… and when you ask anyone over 60, they’ll discuss issues with reminiscence. Their capability to scent declines, however when you give them olfactory enrichment—loads of olfactory stimulation—you may get a dramatic improve of their capability to recollect issues.

Stewart Gandolf (Healthcare Success): There’s a lot to unpack there. I’ll attempt to come again to what you simply stated a minute in the past—as a result of I’d like to speak extra about reversal versus simply slowing, which is thrilling.

However earlier than I get there: once I first met you, we talked about different kinds of sensory stimulation—visible, auditory, tactile, in addition to olfactory and style. We didn’t discuss style a lot, however I’m positive that’s a part of it too.

However I feel over time—even since I’ve identified you—the concentrate on scent appears to be increasingly major. Is {that a} good abstract of your life’s work?

Dr. Michael Leon (Reminiscence Air): Yeah. I feel most individuals discover it stunning as a result of they contemplate the olfactory system their least vital sense. If you happen to ask folks which sense they’d be keen to surrender, virtually everyone says the olfactory system. They suppose it’s only a good factor to find out whether or not the wine you’re consuming is nice.

However the central significance of olfactory stimulation to the well being of your mind is basically not usually appreciated. And due to that, individuals are going by means of their lives with out a lot olfactory stimulation, and their mind begins deteriorating—making it rather more susceptible to all types of different neurological and somatic issues.

Stewart Gandolf (Healthcare Success): Earlier than I get again to the questions we deliberate: I bear in mind speaking about—do I bear in mind this accurately?—that again in your earlier days, you’ll give rats stimulation, reduce them up, and take a look at their brains extra deeply. And those that had rather more stimulation had larger brains.

Is that true? Or was it extra synapses—what was it that you simply discovered within the earlier phases?

Dr. Michael Leon (Reminiscence Air): So what we have been is early studying. It seems that human infants study to be interested in the odor of their mom—or another odor you place involved with them—on the primary day of life. Once they simply come out, that is the very first thing they study concerning the world. And it’s a really highly effective sort of studying.

And it does change their mind. There are anatomical modifications, neurophysiological (electrical) modifications, neurotransmitter modifications, and behavioral modifications. So on the second day of life, you possibly can check them—these human newborns—and so they bear in mind the odor of their mom and so they’re interested in it. And that is, we predict, the primary foundation for the maternal-infant bond.

Stewart Gandolf (Healthcare Success): Wow. Superb. So the environment has modified radically. Has the mind modified too over time—evolutionarily? Is there any proof to that?

Dr. Michael Leon (Reminiscence Air): In our fashionable prosperous world, we simply don’t get a lot olfactory stimulation. And due to that, we’re very susceptible to neurological issues and somatic issues as effectively.

We predict it is a difficult interplay between a rise in irritation that happens within the mind and the physique with out olfactory stimulation. One of many issues that we discovered—and others, lots of of others, have discovered—is that nice odors really lower irritation.

Irritation, as , underlies most of the damaging forces within the mind and physique. And so we predict everyone wants it. And what we’re discovering is that not solely older adults, however middle-aged and youthful adults are actually on this—as a result of everyone needs to have a pointy thoughts. And it seems this may assist folks, we predict, all through their lives.

Stewart Gandolf (Healthcare Success): That’s wonderful.

We’ve talked about folks being sensory-deprived. I’ve to provide a private remark right here—and I don’t suppose I’ve ever informed you this half, Michael. I’ve each a deviated septum and persistent allergic reactions. I’ve taken Claritin, I’ve taken Zyrtec… and I lastly began utilizing the nasal steroid with the allergy spray, with the capsule, and now I can breathe and scent higher. It took that a lot firepower—which stinks—however I can scent issues now.

My spouse is laughing at me as a result of she’ll inform me, “You scent every little thing.” I’m like, “I’ve to—Michael says…”

However I’m experiencing the world totally different as a result of I used to be chronically congested in a single kind or one other for years. I wasn’t fully congested, however my sense of scent has lastly modified. The neti pot helped somewhat, however once I came upon I may do the steroid and the antihistamine on the identical time with out, , dying—it’s been life-changing for me. It actually has.

Dr. Michael Leon (Reminiscence Air): That’s good to know. And it could protect your mind as you become old.

Stewart Gandolf (Healthcare Success): Yeah. So I’ve to share one thing with our viewers right here. I nonetheless have my little vials—and Michael could acknowledge a few of these.

After I had COVID, I known as Michael as a result of I learn about this. I stated, “Michael—they are saying wait six months earlier than you get sensory stimulation. How lengthy ought to I wait?” I’m assuming under no circumstances.

He’s like, “Go to Amazon now and purchase…” Was it rose, lemon, sage, and one thing else? I neglect. However anyway, I purchased them—and I nonetheless have them. It’s wonderful—there’s one thing calming about it. It’s not psychotropic, I don’t suppose, but it surely’s such an instantaneous rush of… I don’t know, emotion.

What’s behind this? Individuals confuse this with aromatherapy, which is sort of associated, however not the identical factor.

Dr. Michael Leon (Reminiscence Air): Over the course of evolution, the mind wants a substantial amount of olfactory stimulation. And as a way to ensure that folks get sufficient, it made us interested in nice odors. So we get an actual rush and a sense of leisure and pleasantness—and we’re attracted to those nice odors.

Actually, you’ve gotten a reflex: while you scent nice odors, you mechanically begin to sniff it with out considering. It’s an actual reflex. And while you’re uncovered to disagreeable odors, the mind stops you from respiration instantly.

Stewart Gandolf (Healthcare Success): Wow—that’s cool.

So we’re going to speak about two issues at the moment. I’d like to speak about autism in somewhat bit as a result of I feel that’s actually vital—and that’s additionally some new stuff arising. However the machine known as Reminiscence Air, so let’s begin there.

Michael and I, by the best way, pitched a present to Hollywood. We had an agent and an legal professional. We really acquired to fulfill with twentieth Tv—and we have been shut, Michael. We have been actually shut. Sometime we’ll do this once more.

However let’s speak concerning the proof about olfactory… You’ve talked about some broad issues, however discuss a number of the scientific proof about olfactory enrichment. Let’s begin with mind well being total after which discuss reminiscence.

Dr. Michael Leon (Reminiscence Air): Okay. I’ll begin with the truth that lab animals are stored in an ordinary field cage alone, with not a lot to do and little or no stimulation. These animals look okay—they will study, bear in mind, have motor expertise, social interactions are regular.

However when you take these rats or mice from an ordinary field cage and put them in a a lot larger enclosure with loads of mates and loads of issues to do, their brains turn out to be rather more complicated and rather more succesful. They study higher, bear in mind higher, have higher motor expertise—every little thing about their habits improves.

Much more spectacular: scientists have made animal fashions of each human neurological dysfunction you possibly can consider. They specific human-type signs after they’re in the usual field cage—little or no stimulation. However while you put them in an enriched atmosphere—larger place, extra mates, extra issues to do—they lose many or all of their neurological signs.

It’s so highly effective {that a} rat injected with a neurotoxin like lead has higher cognitive capability than a rat who hasn’t been injected with any toxin, however resides in an ordinary cage.

So we thought possibly this might profit kids with autism. There’s additionally a state of affairs in Romania with human infants that prompted our curiosity. Throughout Nicolae Ceausescu’s regime, he banned contraceptives and ruined the economic system. Individuals had loads of kids however no cash, so that they introduced them to state orphanages.

Within the orphanages, kids have been put in cages—alone, remoted—identical to rats in laboratories. Once they got here out, relatively than 1%–2% having autism, a few third had autism signs. We predict as a result of they have been residing beneath restricted sensory stimuli.

When some kids have been positioned into full-time foster care—an enriched atmosphere—they misplaced many or all of their autism signs.

So we tried to duplicate this with kids with autism in Irvine. We gave dad and mom a equipment with many odors—plus visible stimulation, auditory stimulation, motor stimulation, and tactile stimulation. We had a management group.

After six months, 42% had a serious enchancment in signs in comparison with 7% with customary care. We additionally discovered an eight-point improve in IQ in comparison with virtually nothing with customary care, elevated receptive language, important enchancment in irregular responses to sensory stimuli. After six months, 21% of significantly affected kids have been not thought of to have traditional autism in comparison with 0% on customary care.

We went on to do different research. One mother or father was so impressed that he fashioned an organization and developed it for folks world wide. It’s known as Mendability, and individuals are utilizing it everywhere in the world with good advantages.

We predict this may be improved additional by giving olfactory enrichment. And we now have a tool the place we predict we are able to do that with none effort.

Stewart Gandolf (Healthcare Success): Earlier than I transfer away from that and begin speaking about reminiscence loss: Michael’s been a really huge a part of my private life.

My daughter—when she was a couple of years previous—started displaying indicators of autism spectrum, and our world simply collapsed. It was terrible. She hadn’t been that method at first and began displaying indicators round two, which I feel is fairly traditional.

Michael launched me to the therapist who innovated this. The wonderful factor… I’ll condense a two- or three-year story: scents like strawberry, after which touching her face—there was one thing about doing that. The primary time we did it, her eyes rolled behind her head. She was the happiest she’d been in months. It was wonderful.

So we did that along with her for years—so long as she allowed us to. She stopped permitting us when she acquired older.

She’s a senior in school. She’s about to graduate. She nonetheless has challenges, however her life trajectory is wildly higher than it will have been with out this. And you could possibly supply me $10 million, Michael, however not expose her to this—and I wouldn’t take it. I wouldn’t return and roll the cube and hope it seems okay. We hear these tales over and over.

Dr. Michael Leon (Reminiscence Air): It actually revolutionizes the best way these kids develop and alters the course of their life. It’s actually vital that folks learn about this as a result of customary care takes months—possibly a 12 months, I’ve heard two years—earlier than you may get a prognosis. Then you definately battle with college techniques and insurance coverage firms to get it funded.

And knowledge from customary care comes from universities, however most individuals don’t get it from universities—they get it from personal firms hiring individuals who could or will not be significantly good. Outcomes aren’t significantly good.

Commonplace care can also be centered simply on social interactions, whereas the enrichment technique offers with all their auxiliary signs, which will be as severe because the social interplay issues.

Stewart Gandolf (Healthcare Success): Yeah. I’ll give the newbie viewpoint on this, Michael.

We determined to do every kind of sensory stimulations. We did imaginative and prescient remedy, studying courses… I took her ice skating when she hated it. Bike using, swimming… However I nonetheless really feel just like the olfactory stimulation with the tactile contact—that was the core of all of it.

We skipped the varsity program solely as a result of they needed to place her in particular ed… one other story. She was type of the star child of her class, and I insisted on common college. We put her in a personal college. Two years later one of many identical lecturers stated, “Oh my God, you made the appropriate choice.”

In order that’s value exploring. And when you’re listening to this on the streaming service, you possibly can go to HealthcareSuccess.com, seek for this podcast. Michael—on the finish of this, it is advisable give me hyperlinks to science for each autism and reminiscence that I can put within the present notes. It’s actually vital. I prefer to make these episodes significant and meaty—not simply listening to us speak, however getting some proof can be superior.

So I shared a really private story there. However like I stated, for hundreds of thousands of {dollars} I wouldn’t spin the bottle and keep away from doing this. It was instantly impactful. I extremely suggest it. I’ve beneficial a number of folks to do that.
And this little bottle of strawberry is a kind of leftovers from these days. I nonetheless have it—possibly 25% left. It goes slowly.

So anyway—let’s discuss reminiscence. The present at the moment is basically about reminiscence, and we’ve acquired one other half hour, so I’m going to spend time on this.

In principle, you could possibly take this little bottle and scent it a number of instances a day and get presumably the identical consequence—it’s simply no one does that, proper?

So the machine—which we’ll discuss in a second—is a method of doing that passively. People—even motivated ones—are horrible at following by means of, Michael.

Dr. Michael Leon (Reminiscence Air): Yeah. An exquisite growth is a examine out of South Korea that used olfactory stimulation to extend the reminiscence of individuals with dementia—Alzheimer’s illness. Individuals have tried every kind of issues; billions of {dollars} spent; lots of of scientific trials. The most recent anti-Alzheimer’s medication are actually ineffective—tiny slowing of decline, nothing you’ll discover. Very costly, unsafe—mind bleeds, mind shrinkage, dying. Onerous to get; it’s a must to go to the hospital for infusions. Worst of all worlds.

Right here you’ve gotten one thing extremely efficient. On 5 assessments of reminiscence, enhancements have been as much as 300% higher than controls. Melancholy signs have been relieved by 325%. Individuals had these enhancements inside 15 days.

The issue is: to get these enhancements, they needed to give them 40 odors twice a day—and no one will do this. Individuals received’t even take low-dose aspirin after a coronary heart assault.
So we devised a tool—we name it Reminiscence Air. It sits in your nightstand and places out 40 nice odors twice an evening. We predict this may revolutionize the best way Alzheimer’s illness is handled.

We’re additionally discovering folks of their 40s and 50s have an interest—they need to hold their minds sharp. We predict individuals are chronically disadvantaged of olfactory stimulation all through their lives, and olfactory enrichment—40 odors twice an evening—will hold the mind wholesome, not only for reminiscence however for emotion and melancholy signs.

The olfactory system has the one devoted superhighway entry to the reminiscence facilities and emotional facilities of the mind. All different senses must undergo aspect streets and consequently don’t have as a lot influence.
So all through life, we predict everyone wants rather more olfactory stimulation, and our machine can present that.

And a pair weeks in the past, Time journal named us as an invention of the 12 months in well being and wellness for 2025. We’ve additionally acquired an award from the American Psychological Affiliation for our work with autism.

Stewart Gandolf (Healthcare Success): That’s wonderful. I’d love all these hyperlinks—give me as many as you need. I’ll put them on there.

Dr. Michael Leon (Reminiscence Air): Okay.

Stewart Gandolf (Healthcare Success): Let’s speak—knowledge you’ve seen, or anecdotes up to now. The machine has gone by means of alpha, beta… a lot of growth. It seems constructing a tool from scratch is tougher than most individuals suppose.

Full disclosure: I’m a minority investor on this product. After working with Michael for all these years, I couldn’t let it go by. So we’ve been speaking about this for 3 or 4 years, proper? Numerous levels of engineering. It takes quite a bit to construct a tool that really works.

Dr. Michael Leon (Reminiscence Air): Yeah. Units are difficult. And it’s not only a machine—it has a disposable. Each month you get a brand new odorant belt with 40 odors, and you place it in as a result of it makes use of up the odors over the course of the month.

All this stuff must be developed individually. Each little half issues. You’re constructing an actual factor. It’s not one molecule—it’s difficult in a dozen methods, possibly a number of dozen methods.

So it’s taken years to get to the purpose the place we are able to manufacture it. Manufacturing is an entire different factor. We tried America—that didn’t work. China—that didn’t work. We lastly discovered three teams in Malaysia, and so they’re doing an impressive job.

We needed to search to search out individuals who would take it significantly and have been competent sufficient to do it precisely proper—as a result of when you’re off by somewhat bit, it’s ineffective.

We lastly employed a gaggle of engineers—former senior Apple designers and engineers—so that they made a phenomenal, useful, manufacturable machine. We’re actually pleased with the way it got here out.

Stewart Gandolf (Healthcare Success): That’s superior. I’m actually glad to listen to that.

Again to the proof: we talked broadly about olfactory. I don’t know if you wish to share anything—or simply anecdotes—as a result of we’re going to do scientific trials ultimately, proper? Any proof you possibly can discuss now about early returns or broadly with Alzheimer’s?

Dr. Michael Leon (Reminiscence Air): One fellow has Parkinson’s illness—and about half of individuals with Parkinson’s develop dementia. After 4 to 6 months on the machine, he took a reminiscence check at the start and after six months. He was a geologist. He greater than doubled his reminiscence rating inside six months. That’s fairly wonderful.

Individuals with Parkinson’s have olfactory loss and elevated irritation—the entire track and dance.

One other individual stated her husband all the time needed to full her sentences as a result of she couldn’t bear in mind the phrase. After a month utilizing Reminiscence Air, he stated, “, I haven’t been having to finish your sentences because you began utilizing this factor.”

Stewart Gandolf (Healthcare Success): I don’t know… that’s good.

Dr. Michael Leon (Reminiscence Air): She additionally stated she was very clumsy—she’d drop a vitamin capsule or a spoon daily. Since utilizing this, she stated she hasn’t dropped something.

There’s a direct connection between the olfactory system and the cerebellum, which controls motor coordination. We predict what we’re doing is making that normalized and wholesome once more.

We’re getting very constructive feedback. Individuals are sleeping a lot better—on common, 22 minutes further sleep, which is big. We predict this will likely turn into actually vital.
As folks become old, deep sleep diminishes, and in lots of older adults there isn’t a lot deep sleep in any respect. Throughout deep sleep, your mind washes out all of the waste that’s accrued—by means of the glymphatic system. It pushes it out to the entrance of the mind and thru the holes within the cranium the place the olfactory system is available in.

In case you have a robust system throughout deep sleep, you possibly can eliminate toxins and waste. However when folks become old, you don’t have this washout as a result of the olfactory system is obstructing the best way. Except you’ve gotten a robust push, it doesn’t get out of the mind.

So that you’re marinating the olfactory system in toxins and waste, which triggers irritation. And irritation accompanies greater than 139 medical issues, neurological and somatic.

We predict many issues impair the lymphatic system so it might probably’t push out waste, and the mind is marinating in its personal waste. That could be why these issues have olfactory dysfunction—as a result of it will increase irritation that damages the olfactory system and prevents waste from being cleared. We predict this could possibly be an vital mechanism to know what’s happening.

Stewart Gandolf (Healthcare Success): Wow—that’s wonderful.

And it’s humorous as a result of I bear in mind instances while you’ve stated, “I’d prefer to imagine that, however the scientist in me doesn’t,” proper?

A few of our listeners are scientists, medical doctors, researchers. What would you say to them in the event that they’re tremendous skeptical? The place would you direct them? I’ll have analysis within the present notes—anything?

Dr. Michael Leon (Reminiscence Air): This is a gigantic literature. There at the moment are 11 main epidemiological research displaying that by midlife, your all-cause mortality—whether or not you die for any cause—will be precisely predicted by your capability to scent issues.

Stewart Gandolf (Healthcare Success): Wow. I’m positive no one is aware of that.

Dr. Michael Leon (Reminiscence Air): And there are about 20 research displaying that when you improve olfactory stimulation—and never only one odor; it’s a number of odors which are vital—you enhance both reminiscence and/or the elements of the mind that management reminiscence.

So it’s not one examine or a pair research—it’s an enormous literature that every one says the identical factor: lack of olfaction damages the mind, and elevated olfactory stimulation will increase mind well being.

Stewart Gandolf (Healthcare Success): So our podcast is basically about innovation and advertising in healthcare. We’ve talked about innovation. I do know you’re not dealing with the advertising, however you’re already promoting these, proper? There’s loads of demand. Any feedback on the advertising?

Dr. Michael Leon (Reminiscence Air): It’s not my space of experience, however we’ve bought out our first cargo. We’ve acquired one other 10,000 approaching a ship. We bought out the primary group with none ads.

There’s been huge curiosity—over 200 media tales world wide: podcasts, TV, radio, newspapers, magazines, on-line—every little thing. Individuals are actually .

I’m fascinated that they’re fascinated. With new concepts, they usually get ignored or individuals are so skeptical they received’t even contemplate them. However right here, individuals are drawn to it. They’re not skeptical—one thing about it hits dwelling.

Stewart Gandolf (Healthcare Success): Our expertise collectively engaged on the machine and program for consuming issues… we’d get constructive science and no one cared. Or the journalistic method is “stability”—at some point a constructive story, the following day 10 folks saying the alternative.

There’s a lot confusion and misinformation on the market. Even with autism—actually arduous.
However with this, what’s the draw back? You’re smelling nice smells at night time. It’s passive.

Dr. Michael Leon (Reminiscence Air): Yeah. And I feel there are some concepts the place folks simply go, “Sure—that is smart.” That is considered one of them.

Different stuff you’ve described, folks go, “Who is aware of—possibly sure, possibly no.”
We actually have the one efficient remedy for anorexia, bulimia, binge consuming dysfunction, and weight problems—even weight problems in kids—and many years later it’s nonetheless not right here.

Stewart Gandolf (Healthcare Success): Yeah—many years later. We labored on that, proper? Many years later, it’s nonetheless not right here. That’s considered one of my most irritating issues professionally. However a minimum of I acquired to put money into Reminiscence Air.

In order we’re wrapping up: it’s about a number of odors. What does it price? What’s the month-to-month factor? How do I purchase it?

Dr. Michael Leon (Reminiscence Air): You go to MemoryAir.com. That’s the one place you may get it at this level—solely in the USA. We don’t have the power to supply it elsewhere. You purchase the machine for $799, and each month you get a brand new odorant belt that’s $39, shipped mechanically. You don’t must do something.

If you get it, you place the odorant belt in, press a button while you fall asleep. After a delay, it’s going to go on and can go on at the moment eternally. You simply get a brand new belt each month as a result of it makes use of up the odors. You place it in, shut the door, and fall asleep. That’s it.

Stewart Gandolf (Healthcare Success): That’s wonderful. And I bear in mind the trials and tribulations of attending to do it that simply. It’s not a simple street—don’t let anyone child you.

And I’m positive availability will change, however proper now it’s MemoryAir.com. I’m actually enthusiastic about this. I get alternatives to put money into issues fairly often, and this is likely one of the only a few the place I did it versus simply common inventory stuff.

However I’m emotionally concerned. I imagine within the concept. I imagine within the science. And I did a horrible job setting this up—I didn’t even inform them about your background with UCI and your professorship and your years of science. However I’ll put that within the present. Be sure you give me a replica of your bio.

Dr. Michael Leon (Reminiscence Air): So Alan will all the time introduce me by saying I’m one of many—in response to a survey from Stanford College Medical College—ranked among the many prime 1% of scientists on this planet.

Stewart Gandolf (Healthcare Success): That’s fairly good.

Dr. Michael Leon (Reminiscence Air): Yeah.

Stewart Gandolf (Healthcare Success): So that you’re not simply promoting stuff. You’re not simply promoting stuff on the carnival .In order that’s… that’s… The rest we missed—knowledge, proof, breakthrough, utility to different illnesses—anything you need to share as we wrap up?

Dr. Michael Leon (Reminiscence Air): The factor that stunned me most is how many individuals who aren’t older adults have an interest and have ordered one—folks of their 30s, 40s, and 50s. Not fairly biohackers—they only need further assist with their mind.

Stewart Gandolf (Healthcare Success): Assuming any individual’s acquired a partner or accomplice—is the machine sturdy sufficient to learn each, or do you purchase two?

Dr. Michael Leon (Reminiscence Air): I like to recommend two as a result of the throw is about 4 ft. Except you sleep on a single mattress, it most likely received’t work for each. If you happen to can afford it, two can be optimum—one on both sides of the mattress.

We now have considered one of these California king beds the place it’s miles between us—so we have now two of them and that works out very well.

Stewart Gandolf (Healthcare Success): I’m going to modify to a twin so I can simply purchase one and be low cost. Probably not.

All proper, Michael—it’s been enjoyable speaking to you. Congratulations. It should be actually thrilling to have your life’s work come collectively into one thing folks can really use.

Dr. Michael Leon (Reminiscence Air): Yeah. It’s an actual pleasure to see it come collectively.

Stewart Gandolf (Healthcare Success): Superior. Thanks.